An antifungal gamma-pyrone and xanthones with monoamine oxidase inhibitory activity from Hypericum brasiliense.

Abstract Text

A new gamma-pyrone (hyperbrasilone), three known xanthones (1,5-dihydroxyxanthone, 5-hydroxy-1-methoxyxanthone and 6-deoxyjacareubin) and betulinic acid have been isolated from a dichloromethane extract of stems and roots of Hypericum brasiliense. Their structures were established by spectroscopic methods (UV, EI-MS, 1H and 13C NMR) and that of the gamma-pyrone was confirmed by X-ray crystallography. Hyperbrasilone and the xanthones were all antifungal against Cladosporium cucumerinum, while the three xanthones showed differing degrees of inhibition of monoamine oxidase A and B.

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2016-09-02 21:22:05

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Citation:- Rocha L, Marston L, Kaplan L, Stoeckli-Evans L, Thull L, Testa L, .An antifungal gamma-pyrone and xanthones with monoamine oxidase inhibitory activity from Hypericum brasiliense. Phytochemistry 1994-Aug;36()1381-5 DOI:



Details of Journal

Journal Title - Phytochemistry

ISSN - 0031-9422

Volume - 36

Issue - 6

Publish date - 1994-Aug

Language - eng

Country - UNITED STATES


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