Are affective disorders associated with alterations of heart rate variability?

Abstract Text

A standardized heart rate analysis was carried out in unmedicated patients with major depression, melancholic type (n = 16), panic disorder (n = 16), reactive depression with suicide attempts during the preceding 24 h (n = 16) and in 16 normal control subjects. The investigations included time- and frequency-derived measurements of heart rate variability. In the patients with reactive depression, no differences could be detected as compared with the control group. The patients with panic disorder showed a significantly increased low-frequency band of spectral analysis (P < 0.01) and a marginally significant increment of heart rate (P = 0.05), probably indicating predominance of sympathetic control of heart rate. In the patients with major depression, we found significantly lower values of heart's beat-to-beat intervals and of the high-frequency peak of spectral analysis than in the other groups (P < 0.025), indicating decreased parasympathetic activity.

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2016-09-02 21:57:32

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Citation:- Rechlin T, Weis T, Spitzer T, Kaschka T, .Are affective disorders associated with alterations of heart rate variability? Journal of affective disorders 1994-Dec;32()271-5 DOI:



Details of Journal

Journal Title - Journal of affective disorders

ISSN - 0165-0327

Volume - 32

Issue - 4

Publish date - 1994-Dec

Language - eng

Country - NETHERLANDS


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