Biochemical indicators of in-hospital complications following pancreatic surgery.

Abstract Text

Early recognition of complications following pancreatic surgery could reduce morbidity and mortality. White cell counts (WCCs), platelets (PLTs), C-reactive protein (CRP) and albumin (ALB) are commonly used as guides in clinical decision making. However, the evidence to support their role as early indicators of complications is unclear. A retrospective cohort analysis of consecutive pancreatic surgical procedures between 2004 and 2008 was performed. Operative procedures, inflammatory markers--WCCs, PLTs, CRP, and ALB--preoperatively and on postoperative days (PODs) 1, 3, 5, 7, 9, 12, and 15, and clinical outcomes were recorded. WCC > 11 x 10(9)/L on POD5 was significantly associated with complications [odds ratio (OR), 2.60; P = 0.0067]. ALB < 28 g/L on POD7 was significantly associated with a postoperative complication (OR, 2.94; P = 0.0031). WCC > 12.2 x 10(9)/L and ALB < or = 28 g/L on POD7 were more likely to be associated with a complication (OR, 4.86; P = 0.0002). Postoperative WCC and ALB levels may be useful as aids to the early diagnosis of complications following pancreatic surgery.

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2016-09-07 22:01:17

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Citation:- John BJ, Wijeyekoon BJ, Warnaar BJ, Shasi BJ, Rahman BJ, Davidson BJ, .Biochemical indicators of in-hospital complications following pancreatic surgery. International surgery -;95()215-20 DOI:



Details of Journal

Journal Title - International surgery

ISSN - 0020-8868

Volume - 95

Issue - 3

Publish date - -

Language - eng

Country - Italy


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